In the same way that there are many different pharmaceuticals available, sterile filling methods also have a variety of applications. Our pharmaceutical filling machine provides first-rate liquid filling, from filling potent substances to guarantee sterile operations and complete process data transparency. With today’s extensive With a range of filling technologies, you can be sure to tackle the most urgent issues.
To help you get the best results possible with precise dosage, we mix tried-and-true methods with cutting-edge digital and automatic approaches. With this, here are different filling systems and benefits a pharmaceutical filling machine may include;
An effective replacement for standard pumps is essential for dosing active biopharmaceutical compounds. The peristaltic technology is one of the most straightforward filling systems of the pharmaceutical filling machine. This is because, it combines accuracy and protection for the filling products. The peristaltic pump is ideal for one-time use filling systems since the product does not come into touch with any equipment parts other than the tubes. You have some leeway in how you approach the safe filling of very powerful medications because typical fill quantities range from 50 microliters to three milliliters.
• Stainless steel (316L) housing, pump head, and roller rotor.
• Excellent for use with biotechnology and other liquid products.
• Single-use tubing throughout the whole product route means high flexibility.
Rolling Diaphragm Pump
This technology is presently in demand for usage in filling processes, especially in the pharmaceutical industry. It enables closed, low-shear filling by consistently moving the product through the pump chamber through a rolling diaphragm. Mainly fill water-like liquids safely, despite their cross-contamination, leaking, cleanliness, and sterilization difficulties. Due to its availability in both stainless steel and single-use type, the rolling diaphragm pump also allows a flexible, small-batch manufacturing process.
• System of closed filling
• Simple to disinfect and sanitize
• Reliable filling quantities
Rotary Valve Piston Pump
The rotary valve piston pump can accurately fill both water-based solutions and very viscous liquids, making it a great option if you need a versatile pump. This simple and accurate filling solution is ideal for non-shear-sensitive materials. In addition to its many uses, the filling system’s design is versatile as it comes in either stainless steel or ceramic. The Smart Pump, an Industry 4.0 solution, can seamlessly integrate with the rotary valve piston pump.
• Driven by a servo motor, which allows for extreme accuracy
• Easy assembly with minimal seals
• CIP/SIP sterilization and cleaning are quick and simple
The creative Smart Pump lays the groundwork for further process data openness. Modern RFID technology transmits crucial information from the piston pump to the filling machine, including the cleaning state, pump position, and correction value. Each filling station is equipped with an RFID reader to do this. Operators may see the data on the filling machine’s control panel. The embedded RFID tag houses all of the data.
• Early discovery of errors
• Safety processes
• A reproducible set of parameters
Mass-flow technology is necessary for precise filling processes. Sensors in the closed system monitor the flow rate, allowing for accurate dosing of the filling volumes. Mass flow is ideal for processing X-ray contrast media, among other things, because of its filling precision and the fact that it can deal with hot or cold filling.
• Quick CIP/SIP intervals
• Highly accurate dosage
• 100% IPC (in-process control) integration
Time-pressure filling systems are excellent for filling complex goods such as suspensions or crystallizing liquids. The filling accuracy may be significantly improved by using specific algorithms. Time-pressure filling, which uses filling sections that can be entirely emptied, maximizes product yields from a mechanical standpoint.
• Better accuracy and efficiency
• General geometry that is user-friendly
• Simple assembly and format modifications
In a pharmaceutical filling machine, multiple products with varied qualities may be filled using the same system. Combining up to four filling stations such as peristaltic, rotary valve piston, rolling diaphragm pump, and time-pressure filling, the combination method offers fl existence on a single platform, allowing for frequent yet brief product changeovers. The innovative filling station’s small footprint and great adaptability make it suitable for tight areas.
• The number of filling stations may vary
• Convenient and adaptable design
• Perfect for systems that need sterility or stainless steel